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Some possible triggers can sometimes include: Using two separate drugs to lose weight naturally can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with fat loss and the individuals who go through it you ought to err to the side of caution and let the FDA do its job and demand some investigation be done so the public understands the side effects and dangers of the medications before we bring them. Keep in mind that drug companies will be in business to earn money and that they would say anything to keep people on his or her medications. Researchers discovered that participants using this drug for a year, lost weight within 4 weeks and have kept the body weight off during the entire 56 weeks in the study. Contrave is really a combination of the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs which are made up of multiple active ingredient, which may make them more efficient and safer. Combo-pilling could be the newest fad or even better the newest to come under scrutiny and thus it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills has become popular will be the fact that as of right now there are no long term prescription weightloss pills that have been licensed by the FDA other than orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications however some of the combinations have been rejected or have yet to be authorized by the FDA. Seizures certainly are a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug may also raise blood pressure levels and heart rate, and really should not be used in those with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure and heartrate and must 't be used in patients with uncontrolled high blood pressure levels, as well as by anyone with heart-related and cerebrovascular (blood vessel dysfunction impacting the brain) disease. Patients with a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients to the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking. New UCLA study on smokers with mental, drug, and alcohol problems